N-bromosuccinimide (nbs)

I. Ubwiza bwabigize umwuga, guhitamo chimie - n - Bromoshincinimide (nbs)

Mu murima munini wa chimie, kubona reagent ikora neza kandi yizewe nurufunguzo rwubushakashatsi bwa siyanse nubushakashatsi bwinganda. N - Bromosuccinimide (nbs), hamwe nibikorwa byingenzi byacyo nibisabwa cyane, byabaye amahitamo yambere kuri chimiste benshi.

II. Umutungo udasanzwe, uyobora imipaka ya chimie

- Ibisubizo byumvikana neza: NBS ni umukozi wingenzi worona muri synthesis. Mu nganda za farumasi, akenshi zikoreshwa nkumukozi wuzuza muri synthesis ya antibiyotike, nka synthesi ya benzyl cephaloporin. Niba ari bromination of olefins cyangwa okidation ya aldehyde kuri bromo - acide, irashobora kugira uruhare rugaragara, itanga ingwate nziza kubwinzira yawe synthesi.

- Umufasha ukomeye wo kumenya ibiyobyabwenge byibanze, bya kabiri, na tertiary **: Nkibitekerezo byo kumenya amashuri abanza, ayisumbuye, na tertiary, bishobora gutandukanya neza ubwoko bwa alcool, bitanga ishingiro ryizewe ryisesengura.

-Ibisigisigi bya okiside: Mu magambo ya okisiden ya tryptophan, NBS arashobora gukina urugero rwiza, mugihe urwego rwa okisine rwa tyrostine, histidine, hamwe nibisigazwa bya metionine bishobora kuba biri hasi. Muri icyo gihe, irashobora kandi gukoreshwa muguhindura amatsinda ya ribososol, atanga ibikoresho bishya kubushakashatsi bwa siyansi.

III. Igenzura rikomeye, umutekano kandi wizewe

- Hejuru - Ibikoresho byiza byibanze: Dukoresha hejuru - ibikoresho byibihe byibanze hamwe nibikorwa bikomeye kugirango byemeze ubuziranenge n'umutekano wa NBS.

- Ububiko butekanye: nbs yunvise ubushuhe. Turasaba kubika muri firigo kugirango tumenye ko imikorere yayo itagira ingaruka. Muri icyo gihe, bigomba kubikwa ukwayo na Aniline, Hydrazine hydrate, peroxide, hamwe nigitekerezo cyo kwirinda ingaruka zitezimbere.

- Igikorwa Cyiza: Mugihe cyo gukoresha, guhumeka cyangwa guhura nuruhukwiye kwirindwa. Mubisanzwe, ibikorwa bigomba gukorwa muri furo ya furo hamwe n'imikorere myiza yo gukora kugirango umutekano wawe ugerweho.

IV. Intera nini ya porogaramu, guhuza ibikenewe bitandukanye

- Umwanya w'ubuvuzi: Mu nganda za farumasi, nbs ntabwo ikoreshwa gusa muri synthesique ya antibiyotike gusa ahubwo irashobora gukoreshwa muguhindura ibiyobyabwenge nka Bromoacetoile, itanga umusanzu mubintu byubuzima bwabantu.

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Guhitamo N - Bromosuccinimide (nbs) bisobanura guhitamo regent yumwuga, ikora neza, kandi umutekano. Reka dukorere hamwe kugirango tugereho ejo hazaza heza mu rwego rwa chimie!