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Milrinone/CAS: 78415-72-2

Short Description:

Product name: Milrinone
CAS: 78415-72-2
MF: C12H9N3O
MW: 211.22
STRUCTURE:


Product Detail

Product Tags

 specification

Item  Specification

 

Appearance off-white powder
melting point >3000C
boiling point 350.9°C
density 1.1922
refractive index 1.5700
storage conditions 2-8°C
Acidity coefficient (pKa) 7.21±0.10

 Usage

New non-glycoside and non-catecholamine cardiotonic drugs have similar effects to amrinone. They have strong positive inotropic effects, which are about 20 to 50 times that of amrinone. They also have obvious effects in dilating vascular smooth muscles, can reduce heart load, and can greatly improve blood supply to the kidneys and muscles. Both oral and intravenous administrations are effective, and there are no serious adverse reactions. They are used for chronic heart failure, congestive heart failure and other severe heart failures.
Cardiotonic drugs have the effects of enhancing myocardial contractility and directly dilating blood vessels.

1. Ventricular arrhythmias, supraventricular arrhythmias, etc. may be observed; a few patients may experience symptoms such as headache, ventricular arrhythmias, weakness, decreased platelet count, etc.; in case of overdose, hypotension and tachycardia may occur; bronchospasm and fever are occasionally seen. 2. It is contraindicated for patients with acute myocardial infarction. 3. It should be used with caution in patients with hypotension, tachycardia, renal insufficiency, atrial fibrillation or flutter (Chemicalbook), electrolyte disorders, drug-induced arrhythmias, kidney diseases, severe aortic or pulmonary valve diseases, etc., pregnant women, and lactating women. 4. The elimination half-life of this product in patients with renal insufficiency is significantly prolonged. Therefore, patients with renal insufficiency should reduce the dosage and slow down the infusion rate. There is no need to adjust the dosage for elderly patients.

Packaging and Shipping

25KG/Drum or as customer requirements.
Belongs to common goods and can deliver by ocean and air

Keep and storage

Shelf life:24 month from date of manufacture in original unopened packaging stored in a cool dry place out of direct sunlight, water.
Ventilated warehouse, Low temperature drying, Separated from oxidants, acids.


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