Methanesulfonyl chloride/CAS：124-63-0

Methanesulfonyl chloride is a compound containing sulfonyl chloride functional groups, commonly used in the synthesis of methylsulfonic acid esters. Methyl sulfonyl chloride is a highly toxic, hygroscopic, corrosive, and tear inducing chemical. This compound needs to be stored in a dry place, preferably in a dryer. In industrial production, it can directly undergo free radical reaction between methane and thionyl chloride.

Usage

Methanesulfonyl chloride can be used as an analytical reagent; It can also be used as a catalyst for esterification and polymerization reactions; Can be used as a raw material for the production of methanesulfonic acid; Can be widely used as synthetic raw materials for pharmaceuticals and pesticides; It can also be used as a stabilizer for liquid sulfur dioxide, a chlorinating agent for anthraquinone and carbazole reduction dyes, a quick drying agent for drying oil inks and coatings, a dyeing improver for polyester, a color regulator for color photos, a condensing agent for xylene, naphthalene and formaldehyde, and a dyeing assistant for wool.

The main use of methylsulfonyl chloride is to prepare methylsulfonyl esters from alcohols, which requires the participation of non nucleophilic bases during the reaction process. Methyl sulfonate esters can be used as intermediates in nucleophilic substitution reactions, elimination reactions, reduction reactions, and rearrangement reactions. When treated with Lewis acid and oxime, the methanesulfonate can undergo Beckmann rearrangement.

Methanesulfonic acid esters can sometimes be used as protecting groups for alcohols, which are stable under acidic conditions and can be deprotected to the alcohol by sodium mercuric acid.

Methanesulfonic acid esters can sometimes be used as protecting groups for alcohols, which are stable under acidic conditions and can be deprotected to the alcohol by sodium mercuric acid.

Methyl sulfonyl chloride can react with amines to form methyl sulfonamide. Unlike methylsulfonyl esters, methylsulfonylamide is a functional group that is highly stable under both acidic and alkaline conditions. If used as a protective group to protect the amino group, lithium aluminum tetrahydroxide or dissolved metal reduction reaction can be used for deprotection.

In the presence of copper chloride, methylsulfonyl chloride can add with alkynes to form β - chlorosulfonyl compounds.

Packaging and Shipping

250KG/Drum or as customer requirements.
Can deliver by ocean and air

Keep and storage

Shelf life:24 month from date of manufacture in original unopened packaging stored in a cool dry place out of direct sunlight, water.
Ventilated warehouse, Low temperature drying, Separated from oxidants, acids.