Imidazole/CAS:288-32-4
specification
Item | Specification |
Appearance | White crystals |
Imidazole(gc)%≥ | ≥99.8 |
Water(kf)% ≤ | 0.2 |
Melting point | 87.5-91.0 |
Usage
purpose
Imidazoles are mainly used as curing agents for epoxy resins, accounting for less than half of the consumption of imidazoles in Japan. The amount of imidazoles is 0.5% -10% of epoxy resins. Imidazoles can be used as antifungal drugs, antifungal agents, hypoglycemic treatments, artificial plasma, etc., and can also be used as treatments, artificial plasma, etc., and can also be used as drugs for the treatment of trichomoniasis and turkey blackhead. Imidazole is one of the main raw materials in the production of imidazole antifungal drugs dichlorfenimidazole, iconazole, ketoconazole, and clotrimazole. Imidazole and 2,4, ω-trichloroacetophenone can be used as the main raw materials to prepare the fruit fungicide imidazole. Add 2,4, ω-trichloroacetophenone to an After the color of the solution gradually disappears, cool to 0 ° C, add imidazole, and stir vigorously for 3h. Then the methanol is evaporated under reduced pressure. The remaining liquid is poured into water and extracted with dichloromethane. After the extraction solution recovers dichloromethane, dilute nitric acid is added to form a salt. After recrystallization with water, it is treated with ammonia to obtain 2 ', 4' -dichloro-2-imidazole acetophenone. Further reduction to the corresponding alcohol with sodium borohydride, and finally in the presence of sodium hydroxide and dimethylformamide, allyl chloride is used to obtain imaizole (Enilconazde, also known as enconazole). The structure and production method of imaizole and dichloramidazole (miconazole) share some similarities. Dichlorobenzimidazole is a broad-spectrum antifungal drug, while imaizole is also an antifungal drug, but it is widely used as a preservative in fruits (also known as Imazalil).
Imidazole can be used as an epoxy resin curing agent, which can improve the mechanical properties of products such as bending, stretching, compression, etc., improve the electrical properties of insulation, and improve the chemical properties of chemical-resistant agents. It is widely used in computers and electrical appliances; as an antirust agent for copper and used in printed circuit boards and integrated circuits; as a pharmaceutical raw material, used in the manufacture of antifungal drugs, antifungal agents, hypoglycemic treatment drugs, artificial plasma, trichomoniasis treatment drugs, bronchial asthma treatment drugs, anti-spot agents, etc.; as a pesticide raw material, used as a synergist for boric acid preparations, the preparation of insecticides and fungicides; in addition, imidazole is also used as a urea-formaldehyde resin curing agent, photographic drugs, adhesives, coatings, rubber vulcanizers, anti-static agents
Determination of cobalt. Organic synthesis. Used for anti-metabolism, anti-histamine. Pharmaceutical and pesticide intermediates, imidazole is an intermediate of pesticides such as imidazole and prochloramide, and is also an intermediate of pharmaceutical antifungal drugs such as dichlorobenzole, econazole, ketoconazole, and clotrimazole. Used as a curing agent for epoxy resins; used as a raw material for imidazole derivatives such as glycopherol and carbonyl diimidazole; an effective buffer in the pH 6.2-7 range; used for titration of aspartic acid and glutamic acid.
Packaging and Shipping
25KG/Drum or as customer requirements.
Belongs to common goods and can deliver by ocean and air
Keep and storage
Shelf life:24 month from date of manufacture in original unopened packaging stored in a cool dry place out of direct sunlight, water.
Ventilated warehouse, Low temperature drying, Separated from oxidants, acids.